From time to time, people on the OTN XMLDB forum, ask if it is possible to connect via the Oracle Protocol Server (aka the Oracle Listener), for instance in combination with APEX and DBMS_EPG. I am not sure if it is an already official supported environment, but the following works as demonstrated in this step-by-step manual
Ingredients
Ingredients needed:
- Oracle RDBMS 10.2.0.3.0 (Enterprise Edition) and/of higher version
- APEX 2.2.1
- Windows 2003 / XP